Curcu-Gel® 325mg BCM-95® Curcugreen® Turmeric Extract 60 Softgels

What is Curcumin? 

Curcumin is the main component in the spice turmeric, and is most studied for its antioxidative and anti-inflammatory properties.  Curcumin has been shown to support a healthy inflammatory response in the body’s heart, blood vessels, arteries and brain^1,2,3,4,5.

While numerous clinical studies report on the vast benefits of curcumin in both animals and humans⁶, the poor oral bioavailability, or amount absorbed by the body, of curcumin may curtail the possible benefits.  

What makes Curcu-Gel™ better? 

Fortunately, Curcu-Gel™ is an enhanced formula that dramatically increasing the bioavailability and sustained retention time of curcumin in the body by using a patent pending curcuminoids complex.  This enhanced formula was found to have increased the bioavailability of curcumin by more than 8 times the standard available curcumin on the market, dramatically increasing the potential for benefit^7,8,9! 

As with all our products, Curcu-Gel™ is manufactured in a certified cGMP facility here in the USA.  Each softgel contains 325mg BCM-95® Curcumin and are free of GMOs, pesticides, soy, gluten, milk and milk by-products, eggs and egg by-products, fish and fish by-products, shell fish, tree nuts, wheat and wheat by-products, peanut and peanut by-products, artificial colors and preservatives.

¹Aggarwal BB, Harikumar KB. “Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases.” Int J Biochem Cell Biol. 2009;41(1):40-59.

²Ono K, Hasegawa K, Naiki H, Yamada M. “Curcumin has potent anti‐amyloidogenic effects for Alzheimer's β‐amyloid fibrils in vitro.” J Neurosci Res. 2004 Mar 15;75(6):742-50.

³Deeb D, Jiang H, Gao X, Al-Holou S, Danyluk AL, Dulchavsky SA, Gautam SC. “Curcumin [1,7-Bis(4-hydroxy-3-methoxyphenyl)-1–6-heptadine-3,5-dione; C21H20O6] Sensitizes Human Prostate Cancer Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand/Apo2L-Induced Apoptosis by Suppressing Nuclear Factor-κB via Inhibition of the Prosurvival Akt Signaling Pathway.” J Pharmacol Exp Ther. 2007 May;321(2):616-25.

⁴Shishodia S, Amin HM, Lai R, Aggarwal BB. “Curcumin (diferuloylmethane) inhibits constitutive NF-kappaB activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma.”Biochem Pharmacol. 2005 Sep 1;70(5):700-13.

⁵Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, Saengsuwan J, Tantayakom K, Laongpech S. “Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study.”Clin Interv Aging. 2014 Mar 20;9:451-8.

⁶Hewlings, Susan J., and Douglas S. Kalman. “Curcumin: A Review of Its’ Effects on Human Health.” Foods 6.10 (2017): 92. PMC. Web. 24 July 2018.

⁷Antony B, Merina B, Lyer V, Judy N, Lennertz K, Joyal S. “A Pilot Cross-Over Study to Evaluate Human Oral Bioavailability of BCM-95? CG (BiocurcumaxTM), A Novel Bioenhanced Preparation of Curcumin.”  Ind Journal of Pharmaceutical Science. 2008; 70(4):445-449.

⁸Shishu, Manjul Maheshwari. “Comparative bioavailability of curcumin, turmeric and Biocurcumax™ in traditional vehicles using non-everted rat intestinal sac model.” Journal of Functional Foods. 2010; 2(1):60-65.

⁹Toden S, Theiss A, Wang X, Goel A. “Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium- induced colitis.” Scientific Reports | 7: 814 | Web 11 April 2017 

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